4-nitro-3-methoxybenzoic acid

4-nitro-3-methoxybenzoic acid - Names and Identifiers

Name	3-Methoxy-4-nitrobenzoic acid
Synonyms	4-Nitro-m-anisic acid 3-methoxy-4-nitrobenzoate 3-Methoxy-4-nitrobenzoic acid 3-Methoxy-4-Mitrobenzoic Acid 4-nitro-3-methoxybenzoic acid 3-METHOXY-4-NITROBENZOIC ACID 4-Nitro-3-methoxybenzoic acid 3-METHOXY-4-NITROBENZOIC ACIID Benzoic acid, 3-methoxy-4-nitro- 4-AMino-3-Methoxybenzoic acid (Methyl, ethyl)
CAS	5081-36-7
EINECS	225-793-2
InChI	InChI=1/C8H7NO5/c1-14-7-4-5(8(10)11)2-3-6(7)9(12)13/h2-4H,1H3,(H,10,11)/p-1

4-nitro-3-methoxybenzoic acid - Physico-chemical Properties

Molecular Formula	C8H7NO5
Molar Mass	197.14
Density	1.5023 (rough estimate)
Melting Point	233-235 °C (lit.)
Boling Point	334.23°C (rough estimate)
Flash Point	198.7°C
Water Solubility	Insoluble in water.
Vapor Presure	2.78E-07mmHg at 25°C
Appearance	Bright yellow crystalline powder
Color	White to Light yellow to Light orange
BRN	2696042
pKa	3.30±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5700 (estimate)
MDL	MFCD00007353

4-nitro-3-methoxybenzoic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	24/25 - Avoid contact with skin and eyes.
UN IDs	Cool, dry,tightly closed
WGK Germany	3
HS Code	29189900

4-nitro-3-methoxybenzoic acid - Introduction

3-Methoxy-4-nitrobenzoic acid is an organic compound with the chemical formula C8H7NO5. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: 3-Methoxy-4-nitrobenzoic acid is an off-white to light yellow crystalline powder.
-Melting point: about 178-182°C.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, chloroform, dimethyl sulfoxide and dichloromethane.

Use:
- 3-Methoxy-4-nitrobenzoic acid is used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
-It can also be used as a raw material for organic dyes.

Preparation Method:
- 3-Methoxy-4-nitrobenzoic acid is usually prepared by the reaction of p-methoxy anisole (3-methoxy benzene ether) and nitric acid. The specific synthetic route can be carried out according to the following steps:
1. The p-methoxyanisole reacts with nitric acid under acidic conditions to generate 3-Methoxy-4-nitrobenzoic acid.
2. The product was purified by distillation to obtain pure 3-Methoxy-4-nitrobenzoic acid.

Safety Information:
- 3-Methoxy-4-nitrobenzoic acid has very limited safety and toxicological information. However, as a chemical substance, appropriate handling and storage measures should be taken to ensure safe use.
-During operation, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves, face masks and protective glasses.
-Avoid contact with skin, eyes or respiratory tract. If contact occurs, rinse immediately with plenty of water and seek medical help.
-Avoid swallowing or inhaling dust-producing substances.
-During storage, it should be kept in a sealed container to avoid contact with oxygen, fire or other flammable substances to prevent fire or explosion.
-For detailed safety operation, please refer to the relevant safety data sheet (MSDS) or consult a professional.

Last Update：2024-04-10 22:29:15